Gastrointestinal Bleeding

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Gastrointestinal Bleeding

Gastrointestinal (GI) bleeding refers to bleeding that occurs anywhere in the digestive tract — from the mouth to the anus. The bleeding may appear as fresh red or coffee-colored blood in vomit or as red, maroon, or black-colored blood in stool, depending on the source and amount of blood loss.

Common Causes of Gastrointestinal Bleeding:

GI bleeding is generally classified as upper or lower depending on the site of origin.


Upper GI Bleeding:

This includes bleeding from the esophagus, stomach, or duodenum.

Esophageal causes:
  • Mallory-Weiss tear (tear in the esophageal lining due to vomiting)
  • Esophageal varices (swollen veins due to liver disease)
  • Esophagitis (inflammation of the esophagus)
  • Esophageal ulcer
  • Esophageal cancer
  • Hiatus hernia with Cameron ulcers

Gastric causes:
  • Gastric ulcer
  • Gastric cancer
  • Gastric varices
  • Gastritis or gastropathy
  • Dieulafoy’s lesion (abnormal blood vessel in the stomach)
  • Gastric antral vascular ectasia (GAVE), also known as “watermelon stomach”

Duodenal causes:
  • Duodenal ulcer
  • Duodenal tumor

Lower GI Bleeding:

This includes bleeding from the small intestine, colon, or anal canal.

Anal canal causes (bright red blood):
  • Hemorrhoids (piles)
  • Anal fissure

Colonic causes:
  • Colonic ulcers due to infection or inflammatory bowel disease (IBD)
  • Colonic polyps or colorectal cancer
  • Angiodysplasia (fragile blood vessels in the colon)
  • Diverticular bleeding

Small intestine causes:
  • Angiodysplasia or telangiectasia
  • Small intestinal tumors
  • Meckel’s diverticulum
  • Ulcerations in the small intestine

Management of GI Bleeding:

Treatment depends on the severity and source of the bleeding.

  • Severe or active bleeding: Patients should be hospitalized and treated with blood transfusions or plasma expanders to stabilize their condition.
  • Mild or chronic bleeding: Can be evaluated and managed in an outpatient setting.

Initial diagnostic tests include:
  • Upper GI endoscopy
  • Colonoscopy

If these are inconclusive, further tests such as CT enterography, CT angiography, capsule endoscopy, or double-balloon enteroscopy may be done to find the bleeding source.

Treatment options depend on the identified cause and may include:
  • Endoscopic ligation for esophageal varices
  • Clipping or Argon Plasma Coagulation (APC) for ulcers or vascular lesions
  • Surgical intervention for tumors or malignancies

In summary, gastrointestinal bleeding is a potentially serious condition that requires identifying the exact site and cause to guide proper treatment and prevent recurrence.

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